Citrate functionalized Mn3O4 in nanotherapy of hepatic fibrosis by oral administration

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Citrate functionalized Mn3O4 in nanotherapy of hepatic fibrosis by oral administration

AIM To test the potential of orally administered citrate functionalized Mn3O4 nanoparticles (C-Mn3O4 NPs) as a therapeutic agent against hepatic fibrosis and associated chronic liver diseases. MATERIALS & METHODS C-Mn3O4 NPs were synthesized and the pH dependent antioxidant mechanism was characterized by in vitro studies. CCl4 intoxicated mice were orally treated with C-Mn3O4 NPs to test its ...

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ژورنال

عنوان ژورنال: Future Science OA

سال: 2016

ISSN: 2056-5623

DOI: 10.4155/fsoa-2016-0029